Padding cleaning device for protein purification

Medicilon's protein scientists have been working on protein expression and purification for many years. We can start your project even you have nothing in hand but the name of your protein. In Medicilon's laboratories, protein purification is performed in scales from micrograms and milligrams. All Protein Purification Services start with the analysis of physico-chemical and biological properties of a target protein resulting in the development of tailored procedures for its extraction, purification and characterization.Email:marketing@medicilon.com.cn Web:www.medicilon.com

The utility model discloses a padding cleaning device for protein purification. The padding cleaning device for the protein purification comprises a funnel 1, a valve 2 is arranged at the position of the neck of the funnel, and a screen mesh 3 is movably connected with the upper edge of the funnel 1 through a clamp 4. Meanwhile, the padding cleaning device for the protein purification achieves the functions of soaking and washing padding through solution, whether pigment washing is thorough or not can be observed visually, and the padding cleaning device for the protein purification is simple in structure, easy to manufacture and convenient to use.

Currently in the field of life sciences, often use filler for protein separation and purification. When the use of fillers used depending on whether the column is divided into chromatographic methods and batch adsorption process in which the former more extensive use. When using chromatographic methods, you need to load the column packing even prepared to become the column, the protein solution was mixed with a flow rate by the time this column selective adsorption and fillers; when using batch adsorption method, you need a filler and direct mixing mixing protein solution, packing the same protein selective adsorption. Since the filler material can be reused, thus purification after the cleaning process takes filler. When using chromatographic methods, packing directly washed in a chromatography column, but poor cleanliness when filling, packing or clogging protein precipitation during the purification process, the cleaning process will make the column pressure, resulting in packing irreversible broken and can not be reused, it needs to be removed from the chromatography column packing, cleaning the outer column; for batch adsorption process, and there are no proper means of packing cleaning.

Utility Model Content

The utility model aims to overcome the deficiencies of the prior art and to provide a protein purification filler cleaning device.

The utility of new technical solutions are outlined below:

A purified protein fillers cleaning apparatus comprising a funnel, the funnel neck is provided with a valve 2, 3 is connected with the screen I of the hopper by clamps 4 along activity.

The mesh aperture particle size is preferably 1 / 3-2 / 3.

This utility model while meeting with the solution soak for filler flush function, to visually observe whether the dye wash thoroughly, is simple in structure, easy to manufacture, easy to use.

Brief Description

FIG. 1 is a schematic view of the implementation of the new structure.

DETAILED DESCRIPTION

The following combination of the utility model is further illustrated by the accompanying drawings.

A purified protein fillers cleaning apparatus comprising a funnel, the funnel neck is provided with a valve 2, 3 is connected with the screen I of the hopper by clamps 4 along activity.

The utility model is a protein purification filler cleaning device suitable for packing in a chromatography column are difficult to clean and use a batch adsorption processes require purified filler cleaning situation.

Below The utility of a novel protein purification filler cleaning device can be connected to a transparent colorless glass container, such as a beaker or bottle, so you can observe the color of the solution is very easy to determine the extent of the filler to be cleaned.

3 mesh to cover to funnel top edge to avoid packing directly discharged from the hopper. [0014] 3 mesh aperture size selection according to particle size, pore size sieve particle size is preferably 1 / 3-2 / 3, in order to prevent the filler loss through the screen, while maximizing the solution discharge speed.

When the filler valve 2 need soaking closed, when the end of the soaking time to open it. After washing, the mesh filler 4 is transferred to save chromatography media container.