GLP big and small mouse upgrowth breeding feed

Medicilon's toxicology department has professional teams with rich experience in toxicology studies. We offer high-quality data and rapid turnaround period to support drug discovery and development. Our toxicological studies are conducted in various animal species. The toxicological evaluation from dose design, in-life studies to histology and pathology testing along with toxicokinetics studies are all compliant with GLP or NON-GLP standards. Our study platform is certified as one of the Shanghai Public Service Research Platforms.Email:marketing@medicilon.com.cn Web:www.medicilon.com

The present invention provides a preparation of breeding feed for rats and mice in accordance with GLP norm, according to the principle of animal nutrition and the character of digestion physiology specifically, the pollutants such as toxin, pesticide, heavy metal etc which are capable of mixing into the feed, are effectively screened, the indexes such as general mineral and heavy metal, organic compounds (including residue of the pesticide), radioactive substances and microorganisms etc, in the feed are controlled effectively within acceptable limits of the GLP norm by preferred feed raw material, reasonable mixture ratio, making the compound feed have credible quality, low price, become an effective compound feed in accordance with the breeding for rats and mice.

The present invention relates to a GLP compliant and mice feed growth and reproduction, belongs to the field of animal nutrition. Background

GLP (Good Laboratory Practice) specification is to ensure drug safety evaluation of international norms, many countries have issued a GLP norms, China in 1993 by the State Science and Technology Commission Director to the 16th order, issued trial regulations in 1999 by the National Drug Supervision Authority on the 14th issued a revised version. It is not only needed to conduct animal experiments hardware conditions such as animal facilities, animal products, the supply of equipment for the infection and other special laboratory facilities and isolation facilities, but also from the software, such as animal rearing facilities maintenance and management, animal husbandry observe the general condition of the animals, dying animals and check processing animal carcasses, etc. by standard operating procedures (SOP) has made clear. Which the animal feed and water should make regular inspections to ensure that they comply with nutritional standards and pollution factors that affect the results below the specified limit, the test results should be saved as raw data. Therefore, in addition to the feed of nutrients such as crude protein, crude fat, energy and other indicators and microbial indicators and other conventional project monitoring, must have the possibility of contamination of feed toxins, pesticides, heavy metals and other pollutants periodic analysis, the purpose is to Feed may affect the results of pollution factors excluded.

At present, the commonly used rats and mice feed can basically meet the growth and reproduction require large mice, even after the high-pressure steam or irradiation sterilization, health indicators which feed partly meet the standards, but the heavy metals and other pollutants are still exceeded and vitamin feed the devastating words, certain amino acid content is also changed, to varying degrees, affect the normal growth and reproduction of rats and mice. In view of this, one GLP norms for the growth and reproduction of rats and mice feed urgent research and development, based on this need, inventors preclinical research laboratory, clinical observational studies of this kind of feed formulations.

The present invention aims to preferred term raw material, a reasonable ratio of the raw materials, the prior art does not improve

To provide a large enough to meet the growth and reproduction of mice required nutrition, health indicators GLP compliant feed. Inventor of corn, flour, wheat bran, soybean, soybean meal, fish meal, calcium hydrogen phosphate, calcium carbonate, vegetable oils, mineral salts premix, vitamin premix made from raw materials with the word material, characterized in that: corn 38- 40 kg, 20-22 kg of flour, bran 4-11 kg, soybeans 5-10 kg, 16-17 kg of soybean meal, fish meal 1-5 kg, 2-3 kg calcium hydrogen phosphate, calcium carbonate 2-3 kg, vegetable oil 0. 5-1 kg, salt 1 kg, 0.8 kg of mineral salt premix, vitamin premix 0. 01-0. 05 kg.