Facilitating a Transaction between a Client

Medicilon has been recognized as one of the top drug discovery contract research organizations (CRO) in China and is managed by a team of scientists with a wealth of experience in US-based pharmaceutical and biotechnology companies. As our areas of expertise and service capabilities continue to expand, more and more pharmaceutical and biotechnology companies have taken advantage of our integrated drug discovery and development services.Email:marketing@medicilon.com.cn Web:www.medicilon.com

Successful life science research service providers and their clients must devote significant time, effort and money to sample management, data management and analysis, accumulating knowledge of publicly accessible standard control samples, web site development, and sales and marketing. Building these essential business functions uses resources that otherwise could be used to develop core research technologies and expand service offerings. Moreover, the absence of these functions often prevents the association of, and subsequent transactions between, life science research providers and their clients.

Therefore, there is a need for companies that can provide these services in an efficient, accurate, and cost effective manner to clients and/or life science research service providers in order to facilitate transactions between clients and life science research service providers. The present invention provides solutions to these and other needs in the art of life sciences.

A reference in this specification to any prior publication (or information derived there from), or to any matter which is known, is not, and should not be taken as an acknowledgement or admission or any form of suggestion that the prior publication (or information derived there from) or known matter forms part of the common general knowledge in the field to which this specification relates.

A functional life science objective refers to a desired assessment goal of a client for a particular test sample requiring the performance of a series of life science research services (e.g., assays) in order to reach the desired assessment goal. The desired assessment goal is related to the life sciences field and answers a functional question regarding the test sample. For example, the sample may be a potential drug. The client may have the assessment goal of determining whether the potential drug is sufficiently non-toxic to file an investigational new drug application (IND) with the Federal Drug Administration (FDA). In this embodiment, the functional life science objective is a preclinical safety study requiring a plurality of assays to assess the safety of the potential drug. Such assays may include, for example, drug-drug interaction assays, cardiotoxicity assays, genotoxicity assays, cell toxicity assays, and target selectivity profiling assays. These safety assays may be performed by one or a plurality of life science research providers, some or all of which may be contacted by the facilitator company in order to fill the client's order.

Because many clients and research providers do not have knowledge of the battery of life science research services required to achieve a functional life science objective, the facilitator company provides valuable knowledge to the client and/or research provider for achieving a given assessment goal of the client. Thus, by identifying particular life science research services required to achieve a requested functional life science objective, and in some embodiments identifying one or more life science research service providers capable of performing one or more of the required life science research services, the facilitator company associates clients with service providers that may otherwise not be associated thereby facilitating transactions between a given client and service provider.

A wide array of life science research objectives may be provided by the facilitator company using the selectable internet-based listing. Appropriate objective include, for example, such as preclinical safety studies, target identification studies, target validation studies, target selectivity profiling studies, drug metabolism studies, biomarker identification studies, chemical optimization studies, drug formulation studies and the like.

Preclinical safety assays include tests designed to evaluate the safety of a potential drug (e.g., a prospective investigational new drug) prior to clinical testing. Preclinical safety studies typically include assays performed with cells and animal models to determine the possible effects of the prospective investigational new drug on the human body in a clinical setting. Target identification studies include tests used to identify one or more molecular or cellular entities that are modulated by a particular chemical or biological test sample (e.g., a prospective drug). Target validation studies include tests designed to confirm or rebut a theory concerning the ability of a chemical or biological sample to modulate one or more molecular or cellular entities. Target selectivity profiling studies include tests to determine whether a particular chemical or biological test sample (e.g., a prospective drug) modulates one or more of a family of related targets (e.g., 10, 100, 500 kinases or all currently known nuclear receptors). Drug metabolism studies include tests to measure the metabolism of a test sample in in vitro assays or in a test animal. Biomarker identification studies include tests to identify surrogate markers for a disease state. Chemical optimization studies include tests to determine optimal chemical synthetic routes for the synthesis of new chemical leads with improved drug properties. Drug formulation studies include tests to identify the optimal salt and crystalline forms of a chemical test sample.