Health care food with assistant blood fat reducing function and preparation method thereof

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First of Ginkgo biloba extract sifting process; materials and sea buckthorn seed oil, garlic oil and oil wax mixture take sieved to prepare a suspension thereof. Take gelatin, glycerin, purified water and caramel color, sol made glue. After the suspension was prepared by pellet machine pellet made of soft capsules, stereotypes, washing and drying pill that prepared according to the invention of soft capsules of health food.

The examples of the health food products, according to the Ministry of Health "health food inspection and evaluation of technical specifications" (2003 edition) evaluation methods of animal function tests and drug safety evaluation test, animals function test results showed that: can significantly lower serum cholesterol levels, increased high-density lipoprotein cholesterol levels, lowering an auxiliary function; toxicological safety evaluation test results were as follows: 1, acute toxicity test: Samples of male and female mice acute oral toxicity test LD50 (95% to confidence limit) are 10300mg / kg; 2, dimensional nuclear test Result: negative; 3, sperm abnormality test: negative; 4, Ames test Result: negative; 30 days feeding test: Test animals grow in good condition, body weight and food utilization normal rate, blood tests, biochemical tests, compared to no significant difference between the main body than dirty and histologic findings with the control group. Safety and Toxicology tests showed the samples safe and nontoxic.

The present invention taken in Example 1 soft capsules, according to the Ministry of Health "health food inspection and evaluation of technical specifications" drug safety evaluation method evaluation test results are as follows:

(1) The acute oral toxicity test results: The sample of male and female mice acute oral toxicity test LD50 greater than 21. 5g / kg;

(2) dimensional nuclear test Result: negative;

(3) sperm abnormality test: negative;

(4) Ames test Result: negative;

(5) 30 days feeding test: Test animals grow well, normal body weight and food utilization, hematology, compared to biochemical tests, mainly dirty body and histological findings than the control group, no significant differences.

Safety and Toxicology tests showed the samples safe and nontoxic.

The present invention taken in Example 1 soft capsules, according to the evaluation method "health food inspection and evaluation of technical specifications" of animal and human tasting test function:

(1) orally administered to mice 0. 38,0. 75,2. 25g / kg BW three different doses of the product 30 days, testing

Changes in serum lipids and cholesterol. Animal function tests results showed that: the experimental group compared with the control group, samples of serum total cholesterol level decreased the difference was significant (P <0.01), serum high-density lipoprotein cholesterol levels increased the difference was significant (P <0.01 ), an auxiliary lowering function.

(2) select 110 cases volunteers meet the standards, according to lipid levels before the test, taking into account the possible age, sex, diet and other factors, were randomly divided into test group and control group taking the test group The soft capsules, 3 times a day, every three; the control group was given a placebo, for taking 45 days. The results showed that: taking the soft capsules 45 days, the average cholesterol fell 0.61 Disabled 0. 43mmol / L, triglycerides fell by an average 0.55 persons 0. 45mmol / L, HDL increased by an average 0.06 persons 0. 13mmol / L, 50 sample testing to meet the requirements of the food group, effective in 38 cases, the total efficiency of 76.0%. Test group of cholesterol, triglycerides between before and after the experiment and the test group and the control group group were significantly different (P <0. 05).

Above Animal and human tasting test results indicated that samples with auxiliary lowering function.