Enzymes found in food and Enzyme-Based Assay in pharmaceuticals

Medicilon provides various enzyme activity assays for kinases, phosphatases, proteinases, deacetylase, peptidase, esterase, and other enzymes. Our line of well-characterized immunoassays and biochemical kits ensures accurate and reproducible results. Email:marketing@medicilon.com.cn Web:www.medicilon.com

Recently, scientists from the European Food Safety Authority (EFSA) on Wednesday announced that they had found a new approach to estimate consumer exposure to enzymes used in food production more accurately, which would improve the safety evaluation of food.

Christina Tlustos, an exposure expert who sits on EFSA's panel on food contact materials, enzymes, flavorings and processing aids, said they have developed an exposure tool which can be tailored to each food process involving food enzymes.

The tool uses technical conversion factors, which means the scientists can combine food consumption data with enzyme use levels and take into account the level of transfer of food enzymes into food products.

Enzymes are protein molecules that catalyze chemical reactions. In the past, they were not considered to be toxic since they were produced naturally by living organisms and present in ingredients used to make food.

However, nowadays, foods are also made using enzymes produced industrially. These enzymes are extracted from plant and animal tissues or produced by fermentation of microorganisms, according to the announcement.

EFSA has received over 300 applications for food enzyme safety evaluations from the European Commission. The use of the new approach paves the way for the evaluation of these applications, it said.

Human and mammals contain 5,000 enzymes. They either dissolve in the cytoplasm, either with a variety of membrane structures, or at specific positions in other structures within the cell. Enzyme-Based Assay is also the important technique in the pharmaceuticals and with more and more pharmaceutical company chooses to look for more professional CRO Company to do this, so it is crucial for them having advanced technique.

Medicilon discovery department owns various kinds of state-of-the-art equipment, such as Envision, Nimbus, Perecion XS etc., and multiple technology platforms for enzyme-based assays, cell-based assays, and radioactive assays, in support of your discovery program optimization. In addition, Medicilon also offer mechanism of action studies, biomarker analysis along with SAR studies, and stable cell lines generation, RNAi and MicroRNA Technologies. Their isotope platform has been certified by the shanghai government.