Protein Crystallization Services

Medicilon established a well-developed structural biology research platform. Medicilon is proud as the first CRO to provide gene to crystal structure service in China. We have well-established integrated service platform, which has been certified as an important platform for drug discovery by Shanghai Government. Email:marketing@medicilon.com.cn Web:www.medicilon.com

The complete three-dimensional structure of proteins and their complexes is a scientific basis for studying the relationship between molecular structure and function in life activities to reveal the physical and chemical properties of life phenomena. X-ray diffraction of proteins and their complex crystals is one of the most important means to study the three-dimensional fine structure of biological macromolecules.

Interdependent with other disciplines, especially by the structural genomics and other hot topics of great drive, Protein crystallization pays more attention to research structure and the interrelationship between functions from the simple analysis of the three-dimensional structure of protein to solve the various types of biological macromolecules and complex structure. In the pharmaceutical research and development, as an important tool for the design of new drugs, the protein crystal structure is widely used in the structure of the new drug design.

Medicilon established a well-developed structural biology research platform. Medicilon is proud as the first CRO to provide gene to crystal structure service in China. We have well-established integrated service platform, which has been certified as an important platform for drug discovery by Shanghai Government. Crystallization and the part it is likely to play in the biotech industry, from development and engineering to manufacturing. And drug delivery is a big part of that future, as crystals can help transport small molecules as well as large biologics to help create viable doses from poorly soluble ingredients.

Medicilon has more than ten years of experiences in providing gene to crystal structure service, including construction design, protein expression and purification, high-throughput screen of crystallization conditions, compound or fragments soaking and structure determination.

Service：

Crystallization condition screen by Mosquito

X-ray diffraction data collection at Synchrone

Co-crystallization of Protein-compound; Fragment screen by soaking or co-crystallization

Determination of structure